Androgens promote the growth of both normal and cancerous prostate cells by binding to and activating the androgen receptor, a protein that is expressed in prostate cells ( 1). Androgens are also necessary for prostate cancers to grow. The most abundant androgens in men are testosterone and dihydrotestosterone (DHT).Īndrogens are required for normal growth and function of the prostate, a gland in the male reproductive system that helps make semen. Hormones circulate in the bloodstream and control the actions of certain cells or organs.Īndrogens (male sex hormones) are a class of hormones that control the development and maintenance of male characteristics. Hormones are substances that are made by glands in the body.
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